MBS219700 | MOUSE ANTI RHODOPSIN

MOUSE ANTI RHODOPSIN | MBS219700 | MyBiosource

Product Short Name: [RHODOPSIN]

Product Name Synonyme: N/A

Other Names: [rhodopsin; Rhodopsin; rhodopsin; rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant); rhodopsin]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [RHO; RHO]

Clonality: Monoclonal

Isotype: IgG1

Clone: [1D4]

Host: Mouse

Reactivity: Amphibia, Mammals

Specificity: This product recognises the sequence TETSQVAPA corresponding to aa 340 to 348 of bovine rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerised to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle.

Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness.

Purity: N/A

Form: Purified
Purified IgG - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunoprecipitation (IP), Immunohistology Paraffin, Western Blot (WB)