MBS214147 | MOUSE ANTI RAT TCR V BETA 16.1

MOUSE ANTI RAT TCR V BETA 16.1 | MBS214147 | MyBiosource

Product Short Name: [TCR V BETA 16.1]

Product Name Synonyme: N/A

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG2b

Clone: [HIS42]

Host: Mouse

Reactivity: N/A

Specificity: This item detects a minor subset of T cells. The subpopulation of HIS 42 positive T cells contains both CD4 and CD8 positive cells, in the same ratio as found in the peripheral T cell population. When bound to Sepharose beads, HIS 42 induces T cell proliferation in the presence of IL-2. In contrast to lymph node T cells a number of thymocytes are found to express HIS 42 only in the cytoplasm or together with membrane expression. Most bright HIS 42 surface labelled thymocytes are also positive for MRC OX-44, a marker predominantly identifying mature thymocytes. SDS PAGE analysis of the membrane molecules immunoprecipitated by HIS 42 shows a band at 85kD. On reduction it separates to two bands at 35kD and 48kD. From this data it is concluded that HIS 42 is directed against a determinant on the rat T cell receptor, which is common to a small number of T cells. Preliminary data suggests that the determinant is found on the beta chain, associated with the Vbeta16.1 gene product.

Purity: N/A

Form: Tissue Culture Supernatant - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Immunohistology Frozen*, Flow cytometry (FC/FACS), Immunoprecipitation (IP)