MBS211102 | MOUSE ANTI HUMAN B CELLS:FITC

MOUSE ANTI HUMAN B CELLS:FITC | MBS211102 | MyBiosource

Product Short Name: [B CELLS ]

Product Name Synonyme: N/A

Other Names: [B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD_antigen: CD20]

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: [MS4A1; MS4A1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; CD20]

Clonality: Monoclonal

Isotype: IgM

Clone: [FMC7]

Host: Mouse

Reactivity: N/A

Specificity: This item recognises a glycoprotein antigen of 105kD expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes, and has been used widely in the study of B cell malignancy. FMC7 has been used extensively to differentiate various types of B cell malignancy. B-CLL is generally considered to be negative for FMC7 expression, but strong staining is seen in many other types of B cell lymphoma, including prolymphocytic leukaemia and hairy cell leukaemia.The nature of the FMC7 antigen has remained poorly defined following its first description in 1981. The expression pattern closely corresponds to that seen with CD22, but studies have shown that FMC7 does not recognise the CD22 molecule itself. A recent publication by Serke et al. has shown that FMC7 recognises a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20.

Purity: N/A

Form: FITC
Purified IgM conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

Concentration: N/A

Storage Stability: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Tested Application: Flow cytometry (FC/FACS)