MBS190376 | Prekallikrein Heavy Chain Monoclonal Antibody

Prekallikrein Heavy Chain Monoclonal Antibody | MBS190376 | MyBiosource

Product Short Name: [Prekallikrein Heavy Chain]

Product Name Synonyme: [Anti-Prekallikrein Heavy Chain; Prekallikrein]

Other Names: N/A

Product Gene Name: N/A

Product Gene Name Synonyme: N/A

Other Gene Names: N/A

Clonality: Monoclonal

Isotype: IgG1

Clone: N/A

Host: Mouse

Reactivity: N/A

Specificity: Anti-Prekallikrein Heavy Chain [MurineMAb recognizes the heavy chain of human prekallikrein.]
This antibody specifically recognizes in human plasma two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%,respectively. This antibody does not cross-react with tissue kallikrein.

Purity: N/A

Form: 200 ug Protein G-purified antibody in PBS, pH 7.4.

Concentration: N/A

Storage Stability: These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

Tested Application: ELISA, Western Blot